Preheat your oven to 375°.
In a large mixing bowl, combine the flour, sugar, baking powder, salt and butter. You can use your electric mixer if you wish but mixing by hand works, too.
In a separate bowl, mix half and half and the egg; fold in the dry ingredients until just combined.
Add the blueberries and stir well, using a large spoon or spatula.
Coat a loaf pan with vegetable oil spray and pour in the batter.
Bake for 30 minutes until the top of cake is golden brown and a toothpick inserted into its center comes out clean.